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Nature of the Cyclol Bond

Authors :
Langmuir, Irving
Wrinch, Dorothy
Source :
Nature; January 1939, Vol. 143 Issue: 3611 p49-52, 4p
Publication Year :
1939

Abstract

THE confirmation by X-ray data1,2of C2, the A 288-residue cage structure proposed for the insulin molecule3, makes it of interest to consider the nature of the cyclol bond, upon the postulation of which this structure and the cyclol theory of protein structure in general4depend.The making and breaking of a cyclol bond between an NH group of a polypeptide chain and a CO group of the same or of another polypeptide chain, requires only the migration of an H atom thus:

Details

Language :
English
ISSN :
00280836 and 14764687
Volume :
143
Issue :
3611
Database :
Supplemental Index
Journal :
Nature
Publication Type :
Periodical
Accession number :
ejs52433888
Full Text :
https://doi.org/10.1038/143049a0