Back to Search
Start Over
Steady-State Pharmacokinetics of Oral Ciprofloxacin in Continuous Cycling Peritoneal Dialysis Patients: Brief Report
- Source :
- Peritoneal Dialysis International; January 2018, Vol. 38 Issue: 1 p73-76, 4p
- Publication Year :
- 2018
-
Abstract
- Steady-state pharmacokinetics of oral ciprofloxacin in 3 continuous cycling peritoneal dialysis (CCPD) outpatients given ciprofloxacin 750 mg b.i.d. for 5 doses was determined. Mean steady-state maximum serum concentration and half-life were 4.4 ±1.5 mg/L and 10.3 ± 2.6 hours, respectively. Mean maximum dialysate concentration in the daytime long dwell and overnight continuous cycling dwell were 7.4 ± 1.2 mg/L and 3.3 ± 1.2 mg/L, respectively. Oral ciprofloxacin 750 mg b.i.d. may be reasonable for bloodstream and peritoneal infections caused by susceptible bacteria in CCPD patients.
Details
- Language :
- English
- ISSN :
- 08968608 and 17184304
- Volume :
- 38
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Peritoneal Dialysis International
- Publication Type :
- Periodical
- Accession number :
- ejs52357916
- Full Text :
- https://doi.org/10.3747/pdi.2017.00052