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Intensive LDL cholesterol-lowering treatment beyond current recommendations for the prevention of major vascular events: a systematic review and meta-analysis of randomised trials including 327 037 participants

Authors :
Wang, Nelson
Fulcher, Jordan
Abeysuriya, Nishan
Park, Laura
Kumar, Shejil
Di Tanna, Gian Luca
Wilcox, Ian
Keech, Anthony
Rodgers, Anthony
Lal, Sean
Source :
The Lancet Diabetes & Endocrinology; January 2020, Vol. 8 Issue: 1 p36-49, 14p
Publication Year :
2020

Abstract

The benefits of LDL cholesterol-lowering treatment for the prevention of atherosclerotic cardiovascular disease are well established. However, the extent to which these effects differ by baseline LDL cholesterol, atherosclerotic cardiovascular disease risk, and the presence of comorbidities remains uncertain.

Details

Language :
English
ISSN :
22138587 and 22138595
Volume :
8
Issue :
1
Database :
Supplemental Index
Journal :
The Lancet Diabetes & Endocrinology
Publication Type :
Periodical
Accession number :
ejs51812016
Full Text :
https://doi.org/10.1016/S2213-8587(19)30388-2