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Orchestrating single-cell analysis with Bioconductor

Authors :
Amezquita, Robert A.
Lun, Aaron T. L.
Becht, Etienne
Carey, Vince J.
Carpp, Lindsay N.
Geistlinger, Ludwig
Marini, Federico
Rue-Albrecht, Kevin
Risso, Davide
Soneson, Charlotte
Waldron, Levi
Pagès, Hervé
Smith, Mike L.
Huber, Wolfgang
Morgan, Martin
Gottardo, Raphael
Hicks, Stephanie C.
Source :
Nature Methods; February 2020, Vol. 17 Issue: 2 p137-145, 9p
Publication Year :
2020

Abstract

Recent technological advancements have enabled the profiling of a large number of genome-wide features in individual cells. However, single-cell data present unique challenges that require the development of specialized methods and software infrastructure to successfully derive biological insights. The Bioconductor project has rapidly grown to meet these demands, hosting community-developed open-source software distributed as R packages. Featuring state-of-the-art computational methods, standardized data infrastructure and interactive data visualization tools, we present an overview and online book (https://osca.bioconductor.org) of single-cell methods for prospective users.

Details

Language :
English
ISSN :
15487091 and 15487105
Volume :
17
Issue :
2
Database :
Supplemental Index
Journal :
Nature Methods
Publication Type :
Periodical
Accession number :
ejs51749367
Full Text :
https://doi.org/10.1038/s41592-019-0654-x