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An endothelial cell-derived growth factor.
- Source :
- The Journal of Cell Biology; May 1980, Vol. 85 Issue: 2 p467-472, 6p
- Publication Year :
- 1980
-
Abstract
- Cell-free plasma-derived serum (PDS) is deficient in the platelet-derived growth factor and will not support the growth of 3T3 cells, fibroblasts, or smooth muscle cells. However, when PDS-containing medium is preincubated with endothelial cells, the medium becomes modified so that it will support growth. The activity produced by the endothelial cells results from a polypeptide of 10,000 to 30,000 daltons which has several features that differ from those of the platelet-derived growth factor, including heat instability and lack of adsorption to CM Sephadex.
Details
- Language :
- English
- ISSN :
- 00219525 and 15408140
- Volume :
- 85
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- The Journal of Cell Biology
- Publication Type :
- Periodical
- Accession number :
- ejs51178377
- Full Text :
- https://doi.org/10.1083/jcb.85.2.467