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The Effects of Dapagliflozin on Systemic and Renal Vascular Function Display an Epigenetic Signature.
- Source :
- The Journal of Clinical Endocrinology & Metabolism; October 2019, Vol. 104 Issue: 10 p4253-4263, 11p
- Publication Year :
- 2019
-
Abstract
- Mechanisms mediating the cardiovascular and renal protection exerted by SGLT2 inhibitors are still partially unknown. We investigated whether dapagliflozin modulates systemic and renal vascular function and structure, and induces epigenetic modifications.
Details
- Language :
- English
- ISSN :
- 0021972X and 19457197
- Volume :
- 104
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- The Journal of Clinical Endocrinology & Metabolism
- Publication Type :
- Periodical
- Accession number :
- ejs51162611
- Full Text :
- https://doi.org/10.1210/jc.2019-00706