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Cardiovascular Safety During and After Use of Phentermine and Topiramate.

Authors :
Ritchey, Mary E
Harding, Abenah
Hunter, Shannon
Peterson, Craig
Sager, Philip T
Kowey, Peter R
Nguyen, Lan
Thomas, Steven
Cainzos-Achirica, Miguel
Rothman, Kenneth J
Andrews, Elizabeth B
Anthony, Mary S
Source :
The Journal of Clinical Endocrinology & Metabolism; February 2019, Vol. 104 Issue: 2 p513-522, 10p
Publication Year :
2019

Abstract

Increases in heart rate were seen during the clinical program for fixed-dose combination phentermine (PHEN) and topiramate (TPM), an oral medication indicated for weight management; however, the effect on cardiovascular (CV) outcomes is uncertain.

Details

Language :
English
ISSN :
0021972X and 19457197
Volume :
104
Issue :
2
Database :
Supplemental Index
Journal :
The Journal of Clinical Endocrinology & Metabolism
Publication Type :
Periodical
Accession number :
ejs51162533
Full Text :
https://doi.org/10.1210/jc.2018-01010