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A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy

Authors :
Torvell, Megan
Hampton, David W.
Connick, Peter
MacLullich, Alasdair M.J.
Cunningham, Colm
Chandran, Siddharthan
Source :
Alzheimer's & Dementia: Translational Research & Clinical Interventions; January 2019, Vol. 5 Issue: 1 p579-591, 13p
Publication Year :
2019

Abstract

Neuroinflammation, which contributes to neurodegeneration, is a consistent hallmark of dementia. Emerging evidence suggests that systemic inflammation also contributes to disease progression.

Details

Language :
English
ISSN :
23528737
Volume :
5
Issue :
1
Database :
Supplemental Index
Journal :
Alzheimer's & Dementia: Translational Research & Clinical Interventions
Publication Type :
Periodical
Accession number :
ejs51153621
Full Text :
https://doi.org/10.1016/j.trci.2019.09.001