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In vivo liposome-mediated transfection of HLA-DR alpha-chain gene into pig hearts.

Authors :
Aleksic, I
Ren, M
Popov, A
Freimark, D
Blanche, C
Czer, L
Trento, A
Barath, P
Source :
European Journal of Cardio-Thoracic Surgery; November 1997, Vol. 12 Issue: 5 p792-797, 6p
Publication Year :
1997

Abstract

Scarcity of suitable donor organs remains a major problem for organ transplantation. Transfer of recipient HLA-genes into animal donor-organs during harvest could induce graft-tolerance without suppressing the recipient immune system.

Details

Language :
English
ISSN :
10107940 and 1873734X
Volume :
12
Issue :
5
Database :
Supplemental Index
Journal :
European Journal of Cardio-Thoracic Surgery
Publication Type :
Periodical
Accession number :
ejs50957654
Full Text :
https://doi.org/10.1016/s1010-7940(97)00247-9