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Neurodevelopmental effects of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children versus HIV-unexposed and uninfected children in Uganda and Malawi: a prospective cohort study

Authors :
Boivin, Michael J
Maliwichi-Senganimalunje, Limbika
Ogwang, Lillian W
Kawalazira, Rachel
Sikorskii, Alla
Familiar-Lopez, Itziar
Kuteesa, Agatha
Nyakato, Mary
Mutebe, Alex
Namukooli, Jackie L
Mallewa, MacPherson
Ruiseñor-Escudero, Horacio
Aizire, Jim
Taha, Taha E
Fowler, Mary G
Source :
The Lancet HIV; August 2019, Vol. 6 Issue: 8 pe518-e530, 13p
Publication Year :
2019

Abstract

Antiretroviral medication during pregnancy and breastfeeding substantially decreases the risk of HIV transmission from mothers to infants, but its effects on the child's neurodevelopment are unknown. This study compared neurodevelopmental outcomes of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children with HIV-unexposed and uninfected children at ages 12, 24, 48, and 60 months.

Details

Language :
English
ISSN :
24054704 and 23523018
Volume :
6
Issue :
8
Database :
Supplemental Index
Journal :
The Lancet HIV
Publication Type :
Periodical
Accession number :
ejs50689153
Full Text :
https://doi.org/10.1016/S2352-3018(19)30083-9