A systems genomics approach identifies SIGLEC15as a susceptibility factor in recurrent vulvovaginal candidiasis

Authors :: Jaeger, M.
Pinelli, M.
Borghi, M.
Constantini, C.
Dindo, M.
van Emst, L.
Puccetti, M.
Pariano, M.
Ricaño-Ponce, I.
Büll, C.
Gresnigt, M. S.
Wang, X.
Gutierrez Achury, J.
Jacobs, C. W. M.
Xu, N.
Oosting, M.
Arts, P.
Joosten, L. A. B.
van de Veerdonk, F. L.
Veltman, J. A.
ten Oever, J.
Kullberg, B. J.
Feng, M.
Adema, G. J.
Wijmenga, C.
Kumar, V.
Sobel, J.
Gilissen, C.
Romani, L.
Netea, M. G.
Source :: Science Translational Medicine; June 2019, Vol. 11 Issue: 496
Publication Year :: 2019
Abstract: SIGLEC15 is a component of the host immune response against Candida albicansand is dysregulated in patients with recurrent vulvovaginal candidiasis.

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