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Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation

Authors :
Koval, Olha M.
Nguyen, Emily K.
Santhana, Velarchana
Fidler, Trevor P.
Sebag, Sara C.
Rasmussen, Tyler P.
Mittauer, Dylan J.
Strack, Stefan
Goswami, Prabhat C.
Abel, E. Dale
Grumbach, Isabella M.
Source :
Science Signaling; April 2019, Vol. 12 Issue: 579
Publication Year :
2019

Abstract

The mitochondrial Ca2+uniporter enables ATP production to match energy demands during the cell cycle.

Details

Language :
English
ISSN :
19450877 and 19379145
Volume :
12
Issue :
579
Database :
Supplemental Index
Journal :
Science Signaling
Publication Type :
Periodical
Accession number :
ejs49949914
Full Text :
https://doi.org/10.1126/scisignal.aav1439