VERDICT MRI for Prostate Cancer: Intracellular Volume Fraction versus Apparent Diffusion Coefficient

Authors :: Johnston, Edward W.
Bonet-Carne, Elisenda
Ferizi, Uran
Yvernault, Ben
Pye, Hayley
Patel, Dominic
Clemente, Joey
Piga, Wivijin
Heavey, Susan
Sidhu, Harbir S.
Giganti, Francesco
O’Callaghan, James
Appayya, Mrishta Brizmohun
Grey, Alistair
Saborowska, Alexandra
Ourselin, Sebastien
Hawkes, David
Moore, Caroline M.
Emberton, Mark
Ahmed, Hashim U.
Whitaker, Hayley
Rodriguez-Justo, Manuel
Freeman, Alexander
Atkinson, David
Alexander, Daniel
Panagiotaki, Eleftheria
Punwani, Shonit
Source :: Radiology; May 2019, Vol. 291 Issue: 2 p391-397, 7p
Publication Year :: 2019
Abstract: The intracellular volume fraction derived from Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumors (VERDICT) MRI enables better differentiation of a Gleason 4 lesion from benign and/or Gleason grade 3+3 lesions in prostate cancer with a high level of repeatability and similar image quality compared with apparent diffusion coefficient values.

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