Back to Search
Start Over
Absolute Configuration and Body Part Distribution of the Alkaloid 6-epi-Monanchorin from the Marine Polychaete Chaetopterus variopedatus
- Source :
- Natural Product Communications; September 2016, Vol. 11 Issue: 9
- Publication Year :
- 2016
-
Abstract
- As a result of the first study on secondary metabolites from the cosmopolitan bioluminescent marine tube polychaete Chaetopterus variopedatus, a new bicyclic guanidine alkaloid, 6-epi-monanchorin (1), along with the previously known monanchorin (2) were isolated. The structure of 1was elucidated by spectroscopic and chemical methods, including a cleavage of the C1–O7bond to obtain a secondary alcohol (3), which was used to determine the absolute configurations by Mosher's method. It was found that 1and 2were mainly accumulated in a secreted mucus special organ of the worm (food net), where green and blue-green microalgae were detected. A biosynthetic pathway to 6-epi-monanchorin and monanchorin from dietary polyenic fatty acid precursors was proposed.
Details
- Language :
- English
- ISSN :
- 1934578X and 15559475
- Volume :
- 11
- Issue :
- 9
- Database :
- Supplemental Index
- Journal :
- Natural Product Communications
- Publication Type :
- Periodical
- Accession number :
- ejs49637688
- Full Text :
- https://doi.org/10.1177/1934578X1601100915