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Fluvoxamine in Prevention of Relapse in Bulimia Nervosa
- Source :
- Journal of Clinical Psychopharmacology; February 1996, Vol. 16 Issue: 1
- Publication Year :
- 1996
-
Abstract
- In a double-blind, placebo-controlled study of 72 patients with bulimia nervosa treated successfully with inpatient psychotherapy, the efficacy of fluvoxamine in maintaining improvement was tested. Fluvoxamine and placebo, respectively, were given over a period of about 15 weeks (2-3 weeks inpatient titration phase, 12 weeks outpatient relapse-prevention [maintenance] phase). The variables assessed concerned bulimic behavior and other aspects of eating disorders, global status, depression, anxieties, obsessive-compulsive behavior, and other aspects of psychopathology. Because the dropout rate was relatively high (N = 27 [33%]) and because it was considerably higher in the fluvoxamine group (19 out of 37 subjects), analyses were performed on the intent-to-treat sample (ideally including all 72 subjects). Results of the completer sample analyses (including only those subjects who finished the study) are briefly presented for comparison.
Details
- Language :
- English
- ISSN :
- 02710749 and 1533712X
- Volume :
- 16
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Journal of Clinical Psychopharmacology
- Publication Type :
- Periodical
- Accession number :
- ejs49427446