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Spectrum of Pulmonary Aspergillosis in Hyper-IgE Syndrome with Autosomal-Dominant STAT3 Deficiency

Spectrum of Pulmonary Aspergillosis in Hyper-IgE Syndrome with Autosomal-Dominant STAT3 Deficiency

Authors :
Duréault, Amélie
Tcherakian, Colas
Poiree, Sylvain
Catherinot, Emilie
Danion, François
Jouvion, Grégory
Bougnoux, Marie Elisabeth
Mahlaoui, Nizar
Givel, Claire
Castelle, Martin
Picard, Capucine
Chansdesris, Marie Olivia
Lortholary, Olivier
Lanternier, Fanny
Coignard, H.
Amazzough, K.
Suarez, F.
Blanche, S.
Sendid, B.
Cornu, M.
Bervar, J.F.
Deschildre, A.
Wemeau, L.
Fieschi, C.
Alanio, A.
Menetrey, C.
Senechal, A.
Ader, F.
Tattevin, P.
Pison, C.
Grandiere-Perez, L.
Garcia-Hermoso, D.
Botterel-Chartier, F.
Source :
The Journal of Allergy and Clinical Immunology: In Practice; July-August 2019, Vol. 7 Issue: 6 p1986-1995.e3
Publication Year :
2019

Abstract

Autosomal-dominant signal transducer and activator of transcription 3 (STAT3) deficiency predisposes to recurrent bacterial pneumonia, complicated by bronchiectasis and cavitations. Aspergillosis is a major cause of morbidity in these patients. However, its diagnosis, classification, and treatment are challenging.

Details

Language :
English
ISSN :
22132198
Volume :
7
Issue :
6
Database :
Supplemental Index
Journal :
The Journal of Allergy and Clinical Immunology: In Practice
Publication Type :
Periodical
Accession number :
ejs49294761
Full Text :
https://doi.org/10.1016/j.jaip.2019.02.041