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STRATEGIES TO MODULATE THE DELETERIOUS EFFECTS OF ENDOTHELIN IN HEPATIC ISCHEMIA-REPERFUSION1

Authors :
Peralta, Carmen
Bulbena, Oriol
Bargalló, Robert
Prats, Neus
Gelpí, Emilio
Roselló-Catafau, Joan
Source :
Transplantation; December 2000, Vol. 70 Issue: 12 p1761-1770, 10p
Publication Year :
2000

Abstract

This study evaluates whether bosentan (endothelin ET receptor antagonist) or preconditioning (mechanism that inhibits the postischemic ET release) could reduce the microvascular disorders and the injurious effects of tumor necrosis factor (TNF) associated with hepatic ischemia-reperfusion (I/R).

Details

Language :
English
ISSN :
00411337 and 15346080
Volume :
70
Issue :
12
Database :
Supplemental Index
Journal :
Transplantation
Publication Type :
Periodical
Accession number :
ejs49279770