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Posttransplant Ischemia-Reperfusion Injury In Transplanted Heart Is Prevented By A Minibody to the Fifth Component of Complement

Authors :
Ferraresso, Mariano
Macor, Paolo
Valente, Marialuisa
Barbera, Mila Della
D’Amelio, Fabio
Borghi, Orietta
Raschi, Elena
Durigutto, Paolo
Meroni, Pierluigi
Tedesco, Francesco
Source :
Transplantation; November 2008, Vol. 86 Issue: 10 p1445-1451, 7p
Publication Year :
2008

Abstract

Complement activation has been implicated in the development of posttransplant ischemia-reperfusion (I/R) which is responsible for the delayed function of 20% to 30% of grafts. C5a and the terminal complement complex (TCC) are the complement activation products mainly involved in tissue injury caused by I/R.

Details

Language :
English
ISSN :
00411337 and 15346080
Volume :
86
Issue :
10
Database :
Supplemental Index
Journal :
Transplantation
Publication Type :
Periodical
Accession number :
ejs49263579
Full Text :
https://doi.org/10.1097/TP.0b013e31818a68e2