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Survival of Allogeneic Self-Assembled Cultured Skin
- Source :
- Transplantation; October 2016, Vol. 100 Issue: 10 p2071-2078, 8p
- Publication Year :
- 2016
-
Abstract
- Porcine allogeneic skin constructs of keratinocytes and fibroblasts without APCs are rejected similarly to normal allogeneic skin. Donors develop anti-MHC I alloantibodies but not anti-MHC II ones. Accelerated rejection to second grafts from MHC-incompatible and compatible donors suggests immunization against minor histocompatibility antigens. Supplemental digital content is available in the text.
Details
- Language :
- English
- ISSN :
- 00411337 and 15346080
- Volume :
- 100
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs49255864
- Full Text :
- https://doi.org/10.1097/TP.0000000000001353