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Tofacitinib Halts Progression of Graft Dysfunction in a Rat Model of Mixed Cellular and Humoral Rejection
- Source :
- Transplantation; July 2018, Vol. 102 Issue: 7 p1075-1084, 10p
- Publication Year :
- 2018
-
Abstract
- Rovira et al report tofacitinib, a Janus kinase 3 inhibitor, reduces T and NK cell infiltration, preserves tubular and glomerular structures, and prevents the progression of allograft dysfunction in a Fisher-to-Lewis rat model of kidney transplantation. Supplemental digital content is available in the text.
Details
- Language :
- English
- ISSN :
- 00411337 and 15346080
- Volume :
- 102
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs49255040
- Full Text :
- https://doi.org/10.1097/TP.0000000000002204