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Alteration of thrornboxane and prostacyclin levels in experimental spinal cord injury
- Source :
- Neurology (Ovid); July 1985, Vol. 35 Issue: 7 p1003-1009, 7p
- Publication Year :
- 1985
-
Abstract
- We measured levels of thromboxane B2and 6-keto-PGF10in rabbit spinal cord and cat CSF after impact injury to spinal cord. Rabbit tiissue thromboxane B2levels increased more than 6-keto-PGF10. In cat, CSF thromboxane B, was higher the first hour postinjury; CSF 6-keto-PGF10also increased, but less so. These results imply activation of arachidonic acid metabolism. The relatively greater increase of thromboxane B, suggests that thromboxane-prostacyclin imbalance may contribute to post-traumatic ischemia.
Details
- Language :
- English
- ISSN :
- 00283878 and 1526632X
- Volume :
- 35
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Neurology (Ovid)
- Publication Type :
- Periodical
- Accession number :
- ejs49041867