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The effect of IFN-1b on the evolution of enhancing lesions in secondary progressive MS

Authors :
Brex, P. A.
Molyneux, P. D.
Smiddy, P.
Barkhof, F.
Filippi, M.
Yousry, T. A.
Hahn, D.
Rolland, Y.
Salonen, O.
Pozzilli, C.
Polman, C. H.
Thompson, A. J.
Kappos, L.
Miller, D. H.
Source :
Neurology (Ovid); December 2001, Vol. 57 Issue: 12 p2185-2190, 6p
Publication Year :
2001

Abstract

After the resolution of contrast enhancement, the majority of new MS lesions become isointense with surrounding white matter on T1-weighted MRI. Less commonly, a hypointense T1 lesion develops, representing the development of more severe focal tissue damage. Interferon beta (IFN) reduces both the number of new enhancing lesions and the duration of contrast enhancement.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
57
Issue :
12
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49033910