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Presenilin-1–associated abnormalities in regional cerebral perfusion

Authors :
Johnson, K.A.
Lopera, F.
Jones, K.
Becker, A.
Sperling, R.
Hilson, J.
Londono, J.
Siegert, I.
Arcos, M.
Moreno, S.
Madrigal, L.
Ossa, J.
Pineda, N.
Ardila, A.
Roselli, M.
Albert, M. S.
Kosik, K.S.
Rios, A.
Source :
Neurology (Ovid); June 2001, Vol. 56 Issue: 11 p1545-1551, 7p
Publication Year :
2001

Abstract

To investigate the influence of the presenilin-1 gene (PS-1) mutation on regional cerebral perfusion, SPECT was evaluated in 57 individuals. The subjects were members of a large pedigree from Colombia, South America, many of whom carry a PS-1mutation for early-onset AD.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
56
Issue :
11
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49033524