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Thalidomide sensory neurotoxicity

Authors :
Cavaletti, G.
Beronio, A.
Reni, L.
Ghiglione, E.
Schenone, A.
Briani, C.
Zara, G.
Cocito, D.
Isoardo, G.
Ciaramitaro, P.
Plasmati, R.
Pastorelli, F.
Frigo, M.
Piatti, M.
Carpo, M.
Source :
Neurology (Ovid); June 2004, Vol. 62 Issue: 12 p2291-2293, 3p
Publication Year :
2004

Abstract

The clinical and neurophysiologic data from 65 patients taking thalidomide were reviewed. Thalidomide sensory neurotoxicity was found to be cumulative dose dependent but occurs only when the total dose is relatively high (>20 g). The risk of developing sensory neuropathy is around 10 below this threshold but increases with higher doses.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
62
Issue :
12
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49026778