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All the 1p19q codeleted gliomas are mutated on IDH1or IDH2(e–Pub ahead of print)

Authors :
Labussière, M.
Idbaih, A.
Wang, X.-W.
Marie, Y.
Boisselier, B.
Falet, C.
Paris, S.
Laffaire, J.
Carpentier, C.
Crinière, E.
Ducray, F.
El Hallani, S.
Mokhtari, K.
Hoang-Xuan, K.
Delattre, J.-Y.
Sanson, M.
Source :
Neurology (Ovid); June 2010, Vol. 74 Issue: 23 p1886-1890, 5p
Publication Year :
2010

Abstract

Recently, the gene encoding the human cytosolic NADPH-dependent isocitrate dehydrogenase (IDH1) was reported frequently mutated in gliomas. Rare mutations were also found in the sequence of the mitochondrial isoform IDH2.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
74
Issue :
23
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49022111
Full Text :
https://doi.org/10.1212/WNL.0b013e3181e1cf3a