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-Amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia

Authors :
Bourgeat, P
Chételat, G
Villemagne, V L.
Fripp, J
Raniga, P
Pike, K
Acosta, O
Szoeke, C
Ourselin, S
Ames, D
Ellis, K A.
Martins, R N.
Masters, C L.
Rowe, C C.
Salvado, O
Source :
Neurology (Ovid); January 2010, Vol. 74 Issue: 2 p121-127, 7p
Publication Year :
2010

Abstract

To investigate whether global and regional -amyloid (A) burden as measured with 11C Pittsburgh compound B (PIB) PET is associated with hippocampal atrophy characterized using MRI in healthy controls and patients with amnestic mild cognitive impairment (aMCI) or Alzheimer disease (AD).

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
74
Issue :
2
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49019767
Full Text :
https://doi.org/10.1212/WNL.0b013e3181c918b5