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Pharmacokinetics of nelfinavir in human immunodeficiency virus-infected infants

Authors :
CAPPARELLI, EDMUND V.
SULLIVAN, JOHN L.
MOFENSON, LYNNE
SMITH, ELIZABETH
GRAHAM, BOBBIE
BRITTO, PAULA
BECKER, MARK I.
HOLLAND, DIANNE
CONNOR, JAMES D.
LUZURIAGA, KATHERINE
Source :
The Pediatric Infectious Disease Journal; August 2001, Vol. 20 Issue: 8 p746-751, 6p
Publication Year :
2001

Abstract

Nelfinavir dosed at ∼20 to 30 mg/kg three times a day (TID) in older children provides exposure similar to 750 mg TID in adults. However, the pharmacokinetics (PK) of nelfinavir in infants who are <2 years of age is not well-described. The objective of this study was to determine the pharmacokinetics of nelfinavir in infants <2 years of age.

Details

Language :
English
ISSN :
08913668 and 15320987
Volume :
20
Issue :
8
Database :
Supplemental Index
Journal :
The Pediatric Infectious Disease Journal
Publication Type :
Periodical
Accession number :
ejs48957349