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Commercial Interferon Gamma Release Assays Compared to the Tuberculin Skin Test for Diagnosis of Latent Mycobacterium tuberculosisInfection in Childhood Contacts in the Gambia

Authors :
Adetifa, Ifedayo M. O.
Ota, Martin O. C.
Jeffries, David J.
Hammond, Abdulrahman
Lugos, Moses D.
Donkor, Simon
Patrick, Owiafe
Adegbola, Richard A.
Hill, Philip C.
Source :
The Pediatric Infectious Disease Journal; May 2010, Vol. 29 Issue: 5 p439-443, 5p
Publication Year :
2010

Abstract

We compared the performance of tuberculin skin test (TST), Quantiferon-TB Gold in-tube (QFT-GIT), and T-SPOT.TBin diagnosing latent tuberculosis (LTBI) among childhood TB contacts in a TB endemic setting with high BCG coverage. We evaluated the performance of interferon gamma release assays (IGRAs) and TST when combined in an algorithm.

Details

Language :
English
ISSN :
08913668 and 15320987
Volume :
29
Issue :
5
Database :
Supplemental Index
Journal :
The Pediatric Infectious Disease Journal
Publication Type :
Periodical
Accession number :
ejs48946975
Full Text :
https://doi.org/10.1097/INF.0b013e3181cb45da