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Oxidative stress after uninephrectomy alters heart morphology in the apolipoprotein E −/− mouse
- Source :
- Journal of Hypertension; November 2008, Vol. 26 Issue: 11 p2220-2229, 10p
- Publication Year :
- 2008
-
Abstract
- Even minor reduction in glomerular filtration rate accelerates atherogenesis and increases cardiovascular risk. The current study on the apolipoprotein E −/− mouse was designed to investigate whether nephron reduction by uninephrectomy causes cardiac remodeling and whether this is prevented by antioxidative treatment.
Details
- Language :
- English
- ISSN :
- 02636352 and 14735598
- Volume :
- 26
- Issue :
- 11
- Database :
- Supplemental Index
- Journal :
- Journal of Hypertension
- Publication Type :
- Periodical
- Accession number :
- ejs48864072
- Full Text :
- https://doi.org/10.1097/HJH.0b013e32830ef5e4