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Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage
- Source :
- Journal of Hypertension; August 2011, Vol. 29 Issue: 8 p1602-1612, 11p
- Publication Year :
- 2011
-
Abstract
- The plasminogen-plasmin system affects tissue fibrosis, presumably by interacting with metalloproteinases (MMPs) and macrophage recruitment. This study tests the influence of plasminogen activator inhibitor-1 (PAI-1) and tissue-type plasminogen activator (tPa) on angiotensin II-mediated hypertensive kidney and heart injury.
Details
- Language :
- English
- ISSN :
- 02636352 and 14735598
- Volume :
- 29
- Issue :
- 8
- Database :
- Supplemental Index
- Journal :
- Journal of Hypertension
- Publication Type :
- Periodical
- Accession number :
- ejs48862449
- Full Text :
- https://doi.org/10.1097/HJH.0b013e32834840e8