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Suicide Gene Therapy With the Yeast Fusion Gene Cytosine Deaminase/Uracil PhosphoribosyltransferaseIs Not Enough for Pancreatic Cancer
- Source :
- Pancreas; October 2007, Vol. 35 Issue: 3 p224-231, 8p
- Publication Year :
- 2007
-
Abstract
- Suicide gene therapy with FCY1gene, encoding cytosine deaminase (CD), together with FUR1, encoding uracil phosphoribosyltransferase (UPRT), has been proposed for pancreatic cancer therapy in vivo. We ascertained whether gene therapy with FCY1-FUR1is effective in killing pancreatic cancer cells after 5-fluorocytosine (5-FC) treatment.
Details
- Language :
- English
- ISSN :
- 08853177 and 15364828
- Volume :
- 35
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Pancreas
- Publication Type :
- Periodical
- Accession number :
- ejs48755776
- Full Text :
- https://doi.org/10.1097/mpa.0b013e3180622519