Effect of Ileal Infusion of Short-Chain Fatty Acids on Pancreatic Prandial Secretion and Gastrointestinal Hormones in Pigs

Nutrients passing the ileum induce mechanisms regulating pancreatic secretion, but the effect of short-chain fatty acids (SCFAs) present in the ileum because of either intestinal fermentation or due to the cecoileal reflux is still unclear. This study investigated the effect of ileal SCFAs on pancreatic secretion and plasma levels of peptide YY, cholecystokinin, motilin, and neurotensin.