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Somatostatin Analog Inhibits the Growth of Insulinoma Cells by p27-Mediated G1 Cell Cycle Arrest

Authors :
Aoki, Takeshi
Motoi, Fuyuhiko
Sakata, Naoaki
Naitoh, Takeshi
Katayose, Yu
Egawa, Shinichi
Miyazaki, Jun-ichi
Unno, Michiaki
Source :
Pancreas; July 2014, Vol. 43 Issue: 5 p720-729, 10p
Publication Year :
2014

Abstract

Although the somatostatin analog octreotide (OCT) has been used for uncontrollable insulinoma, the mechanism involved is still unknown. The aim of this study was to elucidate the therapeutic effect of OCT for insulinoma.

Details

Language :
English
ISSN :
08853177 and 15364828
Volume :
43
Issue :
5
Database :
Supplemental Index
Journal :
Pancreas
Publication Type :
Periodical
Accession number :
ejs48753587
Full Text :
https://doi.org/10.1097/MPA.0000000000000128