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Cholecystokinin Receptor Antagonist Halts Progression of Pancreatic Cancer Precursor Lesions and Fibrosis in Mice
- Source :
- Pancreas; October 2014, Vol. 43 Issue: 7 p1050-1059, 10p
- Publication Year :
- 2014
-
Abstract
- Exogenous administration of cholecystokinin (CCK) induces hypertrophy and hyperplasia of the pancreas with an increase in DNA content. We hypothesized that endogenous CCK is involved in the malignant progression of pancreatic intraepithelial neoplasia (PanIN) lesions and the fibrosis associated with pancreatic cancer.
Details
- Language :
- English
- ISSN :
- 08853177 and 15364828
- Volume :
- 43
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Pancreas
- Publication Type :
- Periodical
- Accession number :
- ejs48753532
- Full Text :
- https://doi.org/10.1097/MPA.0000000000000194