Back to Search
Start Over
PTX3 as a Potential Novel Tool for the Diagnosis and Monitoring of Pulmonary Fungal Infections in Immuno-compromised Pediatric Patients
- Source :
- Journal of Pediatric Hematology / Oncology; December 2008, Vol. 30 Issue: 12 p881-885, 5p
- Publication Year :
- 2008
-
Abstract
- Pentraxin-3 (PTX3) is a member of the long pentraxin superfamily and has a nonredundant role in mediating resistance to fungal pathogens. Serial monitoring of PTX3 plasmatic levels was performed in 10 pediatric leukemia patients affected by pulmonary fungal infections. When compared with values of a control pediatric cohort, PTX3 showed significantly higher plasmatic values. Moreover, the response to the antifungal therapy correlated with normalization of PTX3 values. PTX3 may represent a useful tool for the diagnosis and monitoring of fungal infections in immuno-compromised children.
Details
- Language :
- English
- ISSN :
- 10774114 and 15363678
- Volume :
- 30
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- Journal of Pediatric Hematology / Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs48736476
- Full Text :
- https://doi.org/10.1097/MPH.0b013e318180bc1d