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Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
- Source :
- The Lancet Gastroenterology & Hepatology; May 2019, Vol. 4 Issue: 5 p341-353, 13p
- Publication Year :
- 2019
-
Abstract
- Anti-TNF drugs are effective treatments for the management of Crohn's disease but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors that predict primary non-response at week 14 after starting treatment, non-remission at week 54, and adverse events leading to drug withdrawal.
Details
- Language :
- English
- ISSN :
- 24681253
- Volume :
- 4
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- The Lancet Gastroenterology & Hepatology
- Publication Type :
- Periodical
- Accession number :
- ejs48724801
- Full Text :
- https://doi.org/10.1016/S2468-1253(19)30012-3