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CYP3phylogenomics evidence for positive selection of CYP3A4and CYP3A7

Authors :
Qiu, Huan
Taudien, Stefan
Herlyn, Holger
Schmitz, Juergen
Zhou, Yuan
Chen, Guopei
Roberto, Roberta
Rocchi, Mariano
Platzer, Matthias
Wojnowski, Leszek
Source :
Pharmacogenetics and Genomics; January 2008, Vol. 18 Issue: 1 p53-66, 14p
Publication Year :
2008

Abstract

CYP3A metabolizes 50 of currently prescribed drugs and is frequently involved in clinically relevant drug interactions. The understanding of roles and regulations of the individual CYP3Agenes in pharmacology and physiology is incomplete.

Details

Language :
English
ISSN :
17446872 and 17446880
Volume :
18
Issue :
1
Database :
Supplemental Index
Journal :
Pharmacogenetics and Genomics
Publication Type :
Periodical
Accession number :
ejs48719375
Full Text :
https://doi.org/10.1097/FPC.0b013e3282f313f8