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The unique complexity of the CYP3A4upstream region suggests a nongenetic explanation of its expression variability
- Source :
- Pharmacogenetics and Genomics; January 2010, Vol. 20 Issue: 1 p167-178, 12p
- Publication Year :
- 2010
-
Abstract
- The individually variable and unpredictable expression of CYP3A4compromises therapies with 50 of contemporary drugs. Gene variants explain only a fraction of this variability.
Details
- Language :
- English
- ISSN :
- 17446872 and 17446880
- Volume :
- 20
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Pharmacogenetics and Genomics
- Publication Type :
- Periodical
- Accession number :
- ejs48719223
- Full Text :
- https://doi.org/10.1097/FPC.0b013e328336bbeb