Back to Search
Start Over
Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke
- Source :
- Pharmacogenetics and Genomics; August 2008, Vol. 18 Issue: 8 p677-682, 6p
- Publication Year :
- 2008
-
Abstract
- Genetic polymorphisms are associated with lipid-lowering response to statins, but generalizeability to disease endpoints is unclear. The association between 82 common single nucleotide polymorphisms (SNPs) in six lipid-related or statin-related genes (ABCB1, CETP, HMGCR, LDLR, LIPC, NOS3) and incident nonfatal myocardial infarction (MI) and ischemic stroke was analyzed according to current statin use and overall in a population-based case–control study (856 MI, 368 stroke, 2686 controls).
Details
- Language :
- English
- ISSN :
- 17446872 and 17446880
- Volume :
- 18
- Issue :
- 8
- Database :
- Supplemental Index
- Journal :
- Pharmacogenetics and Genomics
- Publication Type :
- Periodical
- Accession number :
- ejs48718729
- Full Text :
- https://doi.org/10.1097/FPC.0b013e3283033528