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In Vitroand In VivoStudies of Spironolactone as an Antischistosomal Drug Capable of Clinical Repurposing

Authors :
Guerra, Rafael A.
Silva, Marcos P.
Silva, Tais C.
Salvadori, Maria C.
Teixeira, Fernanda S.
de Oliveira, Rosimeire N.
Rocha, Jefferson A.
Pinto, Pedro L. S.
de Moraes, Josué
Source :
Antimicrobial Agents and Chemotherapy; December 2018, Vol. 63 Issue: 3
Publication Year :
2018

Abstract

Schistosomiasis is a parasitic flatworm disease that infects over 200 million people worldwide, especially in poor communities. Treatment and control of the disease rely on just one drug, praziquantel.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
63
Issue :
3
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs48697905
Full Text :
https://doi.org/10.1128/AAC.01722-18