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Inosine Triphosphatase Polymorphisms and Ribavirin Pharmacokinetics as Determinants of Ribavirin-Associate Anemia in Patients Receiving Standard Anti-HCV Treatment
- Source :
- Therapeutic Drug Monitoring; April 2012, Vol. 34 Issue: 2 p165-170, 6p
- Publication Year :
- 2012
-
Abstract
- Functional variants of inosine triphosphatase (ITPA) were recently found to protect against ribavirin (RBV)-induced hemolytic anemia. However, no definitive data are yet available on the role of plasma RBV concentrations on hemoglobin (Hb) decrement. Moreover, no data have been published on the possible interplay between these 2 factors.
Details
- Language :
- English
- ISSN :
- 01634356 and 15363694
- Volume :
- 34
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Therapeutic Drug Monitoring
- Publication Type :
- Periodical
- Accession number :
- ejs48550552
- Full Text :
- https://doi.org/10.1097/FTD.0b013e31824bf778