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Disruption of Nrf2 exacerbated the damage after spinal cord injury in mice

Authors :
Mao, Lei
Wang, Han-Dong
Wang, Xiao-Liang
Tian, Lei
Xu, Jian-Ya
Source :
The Journal of Trauma; January 2012, Vol. 72 Issue: 1 p189-198, 10p
Publication Year :
2012

Abstract

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcriptional factor for antioxidant response element-regulated genes. After spinal cord injury (SCI), the Nrf2-antioxidant response element pathway is activated in the spinal cord. However, the function of Nrf2 after SCI has not yet been studied.

Details

Language :
English
ISSN :
00225282
Volume :
72
Issue :
1
Database :
Supplemental Index
Journal :
The Journal of Trauma
Publication Type :
Periodical
Accession number :
ejs48508904
Full Text :
https://doi.org/10.1097/TA.0b013e31821bf541