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A systematic review of the literature reporting on randomised controlled trials comparing treatments for faecal incontinence in adults
- Source :
- Acta Chirurgica Belgica; January 2019, Vol. 119 Issue: 1 p1-15, 15p
- Publication Year :
- 2019
-
Abstract
- AbstractAim:To perform a review of the literature reporting on randomised controlled trials (RCTs) comparing treatments for faecal incontinence (FI) in adults.Methods:A literature search of MEDLINE, Embase, Science Citation Index Expanded and Cochrane was performed in order to identify RCTs reporting on treatments for FI.Results:The review included 60 RCTs reporting on 4838 patients with a mean age ranging from 36.8 to 88 years. From the included RCTs, 32 did not identify a significant difference between the treatments compared. Contradictory results were identified in RCTs comparing percutaneous posterior tibial nerve stimulation and transcutaneous tibial nerve stimulation versus sham stimulation, biofeedback-pelvic floor muscle training (BF-PFMT) versus PFMT, and between bulking agents such as PTQTMversus Durasphere®. In two separate RCTs, combination treatment of amplitude-modulated medium frequency stimulation and electromyography-biofeedback (EMG-BF), was noted to be superior to EMG-BF and low-frequency electrical stimulation alone. Combination of non-surgical treatments such as BF with sphincteroplasty significantly improved continence scores compared to sphincteroplasty alone. Surgical treatments were associated with higher rates of serious adverse events compared to non-surgical interventions.Conclusions:The current evidence has not identified significant differences between treatments for FI, and where differences were identified, the results were contradictory between RCTs.
Details
- Language :
- English
- ISSN :
- 00015458
- Volume :
- 119
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Acta Chirurgica Belgica
- Publication Type :
- Periodical
- Accession number :
- ejs48371224
- Full Text :
- https://doi.org/10.1080/00015458.2018.1549392