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Peripheral blood IRF1expression as a marker for glucocorticoid sensitivity
- Source :
- Pharmacogenetics and Genomics; March 2015, Vol. 25 Issue: 3 p126-133, 8p
- Publication Year :
- 2015
-
Abstract
- Despite of the common usage of glucocorticoids (GCs), a significant portion of asthma patients exhibit GC insensitivity. This could be mediated by diverse mechanisms, including genomics. Recent work has suggested that measuring changes in gene expression may provide more predictive information about GC insensitivity than baseline gene expression alone, and that expression changes in peripheral blood may be reflective of those in the airway.
Details
- Language :
- English
- ISSN :
- 17446872 and 17446880
- Volume :
- 25
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Pharmacogenetics and Genomics
- Publication Type :
- Periodical
- Accession number :
- ejs48357781
- Full Text :
- https://doi.org/10.1097/FPC.0000000000000116