Back to Search Start Over

MicroRNA-200c Contributes to Injury From Transient Focal Cerebral Ischemia by Targeting Reelin

Authors :
Stary, Creed M.
Xu, Lijun
Sun, Xiaoyun
Ouyang, Yi-Bing
White, Robin E.
Leong, Jason
Li, John
Xiong, Xiaoxing
Giffard, Rona G.
Source :
Stroke (Ovid); February 2015, Vol. 46 Issue: 2 p551-556, 6p
Publication Year :
2015

Abstract

MicroRNA (miR)-200c increases rapidly in the brain after transient cerebral ischemia but its role in poststroke brain injury is unclear. Reelin, a regulator of neuronal migration and synaptogenesis, is a predicted target of miR-200c. We hypothesized that miR-200c contributes to injury from transient cerebral ischemia by targeting reelin.

Details

Language :
English
ISSN :
00392499 and 15244628
Volume :
46
Issue :
2
Database :
Supplemental Index
Journal :
Stroke (Ovid)
Publication Type :
Periodical
Accession number :
ejs48324423
Full Text :
https://doi.org/10.1161/STROKEAHA.114.007041