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The X-Chromosome Has a Different Pattern of Gene Expression in Women Compared With Men With Ischemic Stroke

Authors :
Stamova, Boryana
Tian, Yingfang
Jickling, Glen
Bushnell, Cheryl
Zhan, Xinhua
Liu, Dazhi
Ander, Bradley P.
Verro, Piero
Patel, Vihar
Pevec, William C.
Hedayati, Nasim
Dawson, David L.
Jauch, Edward C.
Pancioli, Arthur
Broderick, Joseph P.
Sharp, Frank R.
Source :
Stroke (Ovid); February 2012, Vol. 43 Issue: 2 p326-334, 9p
Publication Year :
2012

Abstract

Differences in ischemic stroke between men and women have been mainly attributed to hormonal effects. However, sex differences in immune response to ischemia may exist. We hypothesized that differential expression of X-chromosome genes in blood immune cells contribute to differences between men and women with ischemic stroke.

Details

Language :
English
ISSN :
00392499 and 15244628
Volume :
43
Issue :
2
Database :
Supplemental Index
Journal :
Stroke (Ovid)
Publication Type :
Periodical
Accession number :
ejs48320927
Full Text :
https://doi.org/10.1161/STROKEAHA.111.629337