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High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of Mycobacterium ulceransDisease
- Source :
- Antimicrobial Agents and Chemotherapy; November 2018, Vol. 63 Issue: 2
- Publication Year :
- 2018
-
Abstract
- Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a neglected tropical skin and soft tissue infection that is associated with disability and social stigma. The mainstay of BU treatment is an 8-week course of rifampin (RIF) at 10 mg/kg of body weight and 150 mg/kg streptomycin (STR).
Details
- Language :
- English
- ISSN :
- 00664804 and 10986596
- Volume :
- 63
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Antimicrobial Agents and Chemotherapy
- Publication Type :
- Periodical
- Accession number :
- ejs48267052
- Full Text :
- https://doi.org/10.1128/AAC.01478-18