THE EFFECTS OF ADRENALECTOMY AND HYPOPHYSECTOMY ON BILE FLOW IN THE RAT

Using a method which permits bile collection relatively free from stress or trauma, we have studied bile flow in normal and hypophysectomized rats. Hypophysectomy was found to result in a sharply reduced bile flow which was not increased by small doses of corticosterone or of deoxycorticosterone. Adrenalectomy, previously reported to have a similar effect, was found not to reduce bile flow in either of the two strains of rats studied.