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Degradation of epidermal growth factor receptors by cathepsin L‐like protease: Inhibition of the degradation by c‐Ha‐rasgene products
- Source :
- FEBS Letters; June 1988, Vol. 233 Issue: 2 p367-370, 4p
- Publication Year :
- 1988
-
Abstract
- Extract of N1H3T3 mouse fibroblasts contains a protease which can cleave epidermal growth factor receptor (EGF receptor). This protease was tentatively named cathepsin X and purified to near homogeneity. The characteristics of cathepsin X were similar to those of cathepsin L and the proteolytic activity of cathepsin X was inhibited by c‐Ha‐rasgene products.
Details
- Language :
- English
- ISSN :
- 00145793
- Volume :
- 233
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- FEBS Letters
- Publication Type :
- Periodical
- Accession number :
- ejs46720683
- Full Text :
- https://doi.org/10.1016/0014-5793(88)80462-9