Back to Search
Start Over
S‐100b protein regulates the activity of skeletal muscle adenylate cyclase in vitro
- Source :
- FEBS Letters; November 1988, Vol. 240 Issue: 1-2 p177-180, 4p
- Publication Year :
- 1988
-
Abstract
- We have investigated the effect of the b isoform of S‐100 proteins on adenylate cyclase activity of rat skeletal muscle. S‐100b inhibits the adenylate cyclase activity in the presence of Mg2+(5.0–50 mM), while it activates the same enzyme in the presence of Ca2+(0.1–1.0 mM) dose‐dependently in both cases. S‐100b counteracts the stimulatory effect of NaF on adenylate cyclase in the presence of Mg2+and the inhibitory effect of RMI 12330 A in the presence of Ca2+.
Details
- Language :
- English
- ISSN :
- 00145793
- Volume :
- 240
- Issue :
- 1-2
- Database :
- Supplemental Index
- Journal :
- FEBS Letters
- Publication Type :
- Periodical
- Accession number :
- ejs46707302
- Full Text :
- https://doi.org/10.1016/0014-5793(88)80363-6